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PTGX Protagonist Therapeutics, Inc.

NASDAQ Global Market · Biotechnology · Healthcare

$155.10
+3.68 (+2.43%)

Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to discovering and advancing peptide-based therapies. Their research primarily focuses on treatments for hematological and blood conditions, as well as inflammatory and immune-mediated disorders. The company's pipeline features rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials for …

Market Cap: $9.97Bwww.protagonist-inc.com

Price (90d)

No price history yet — the daily price refresh runs once a day.

Signal Score (90d)

120
120
Aug 12Aug 12

Quote

Day Range
$149.17 – $155.53
52-Week Range
$54.50 – $155.53
Volume
$397.7K
Market Cap
$9.97B
50-Day Avg
$128.88
200-Day Avg
$100.79
Prev Close
$151.42
Open
$150.23

Valuation & Ratios

P/E Ratio
-42.60
EPS
$-2.05
P/B Ratio
9.03
P/S Ratio
120.66
Debt/Equity
0.02
Current Ratio
12.71
Dividend Yield
+0.0%
Gross Margin
+97.3%

Returns & Efficiency

Return on Equity
-21.2%
Return on Assets
-19.4%
FCF Yield
+1.0%
EV/EBITDA
-42.43

Revenue & Net Income (Annual)

Fiscal YearRevenueNet IncomeEPS
2025$46.02M$-130.15M$-2.05
2024$434.43M$275.19M$4.47
2023$60.00M$-78.95M$-1.39
2022$26.58M$-127.39M$-2.52
2021$27.36M$-125.55M$-2.65

Social Signal Score

70
5d
70
1 mentions
30d
70
1 mentions
60d
70
1 mentions
90d
70
1 mentions
news: 1

Earnings

Thu, Nov 5(in 3 months)

Consensus estimate $2.19 per share

4of 7 quarters beat consensus

Typical surprise +0.9% (median, so one quarter with a near-zero estimate can't distort it)

  • Wed, Aug 5$2.29 vs $2.27beat
  • Tue, May 5$0.05 vs $-0.65beat
  • Wed, Feb 25$-0.69 vs $-0.53miss
  • Thu, Nov 6$-0.62 vs $-0.59miss
  • Wed, Aug 6$-0.55 vs $-0.53miss
  • Tue, May 6$-0.19 vs $-0.50beat

Estimates and results for PTGX via Financial Modeling Prep. Beating consensus says the company cleared the bar analysts set, not that the business grew.

Valuation

PTGXhas no positive reported earnings per share, so an earnings-multiple projection can't be built for it. Companies are valued on other measures at this stage — revenue growth, cash burn, or book value — none of which this calculator models.

Mentions (1)

  • Newsseekingalpha.com·3d ago·Positive

    Protagonist Therapeutics: "Strong Buy" ICOTYDE FDA Approval And PN-881 Advancement Protagonist Therapeutics (PTGX) maintains a "Strong Buy" rating, driven by FDA approval of ICOTYDE for moderate-to-severe plaque psoriasis and strong partnership economics. Company is advancing rusfertide for polycythemia vera, with FDA Priority Review decision expected August 2026 and substantial milestone and royalty potential from Takeda. Development pipeline includes oral IL-17 antagonist PN-881 for psoriasis

    View source ↗