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SPRO Spero Therapeutics, Inc.

NASDAQ Global Select · Biotechnology · Healthcare

$1.23
-0.01 (-0.81%)

Spero Therapeutics, Inc. is a biopharmaceutical firm in the clinical development stage, primarily focused on discovering, advancing, and commercializing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases within the United States. The company's pipeline includes several key therapeutic candidates: tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-clas…

Market Cap: $71.22Msperotherapeutics.com

Price (90d)

No price history yet — the daily price refresh runs once a day.

Signal Score (90d)

107
107
Aug 12Aug 12

Quote

Day Range
$1.19 – $1.25
52-Week Range
$1.08 – $3.08
Volume
$744.5K
Market Cap
$71.22M
50-Day Avg
$1.86
200-Day Avg
$2.31
Prev Close
$1.24
Open
$1.25

Valuation & Ratios

P/E Ratio
15.53
EPS
$0.15
P/B Ratio
2.21
P/S Ratio
2.19
Debt/Equity
0.05
Current Ratio
7.59
Dividend Yield
+0.0%
Gross Margin
+100.0%

Returns & Efficiency

Return on Equity
+14.5%
Return on Assets
+12.4%
FCF Yield
-9.7%
EV/EBITDA
10.55

Revenue & Net Income (Annual)

Fiscal YearRevenueNet IncomeEPS
2025$59.62M$8.57M$0.15
2024$47.98M$-68.57M$-1.27
2023$103.78M$22.81M$0.43
2022$48.58M$-46.41M$-1.23
2021$3.07M$-89.76M$-2.91

Social Signal Score

58
5d
58
3 mentions
30d
58
3 mentions
60d
58
3 mentions
90d
58
3 mentions
news: 3

Earnings

Thu, Nov 12(in 3 months)

Consensus estimate $-0.16 per share

6of 7 quarters beat consensus

Typical surprise +48.0% (median, so one quarter with a near-zero estimate can't distort it)

  • Wed, Aug 12$-0.16 vs $-0.17beat
  • Wed, May 13$-0.13 vs $-0.18beat
  • Thu, Mar 26$0.53 vs $-0.20beat
  • Thu, Nov 13$-0.13 vs $-0.25beat
  • Tue, Aug 12$-0.03 vs $-0.38beat
  • Tue, May 13$-0.25 vs $-0.55beat

Estimates and results for SPRO via Financial Modeling Prep. Beating consensus says the company cleared the bar analysts set, not that the business grew.

Valuation

Project earnings forward and see what return today's price implies.

EPS was negative in at least one boundary year, so a compound growth rate can't be computed from it. Set your own assumption.

EPS in 5 years
$0.22
Implied price
$3.60
Return from $1.23
23.9% a year

To earn 15.0% a year on these assumptions you'd need to buy at $1.79 — today's price is already 31.2% below that.

How sensitive is that answer?

Annual return across nearby assumptions. If the result is only attractive in one corner, that is the finding.

growth \ P/E1214161820
-2.0%6.2%9.5%12.5%15.1%17.6%
3.0%11.6%15.1%18.2%21.0%23.6%
8.0%17.0%20.7%23.9%26.9%29.6%
13.0%22.4%26.3%29.7%32.8%35.6%
18.0%27.8%31.8%35.4%38.6%41.6%

This is arithmetic on assumptions you chose, not a forecast or a recommendation. It ignores dividends, buybacks, share issuance and debt, and it assumes a company still earning money in 5 years. Change any input and the answer changes a lot — that sensitivity is the honest result, not a flaw in the model.

Mentions (3)

  • Newsseekingalpha.com·2d ago·Positive

    Spero Therapeutics, Inc. (SPRO) Q2 2026 Earnings Call Transcript Spero Therapeutics, Inc. (SPRO) Q2 2026 Earnings Call Transcript

    View source ↗
  • Newsmarketbeat.com·2d ago·Neutral

    Spero Therapeutics Q2 Earnings Call Highlights Spero Therapeutics NASDAQ: SPRO used its second-quarter update to outline a strategic shift toward immune-mediated diseases, supported by the FDA approval of Utebzi and a new licensing agreement for SP001, an antibody candidate the company plans to develop initially for IgG4-related disease.

    View source ↗
  • Newsglobenewswire.com·2d ago·Neutral

    Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update CAMBRIDGE, Mass., Aug. 12, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and inflammation, today announced financial results for the second quarter ended June 30, 2026, and provided a corporate update.

    View source ↗